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|Tested species reactivity||Human, Mouse, Rat|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Contains||0.09% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||1:50-1:100|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 1 publications below|
MA1-34345 has been successfully used in immunohistochemistry (frozen tissue) and immunohistochemistry (paraffin tissue) applications. Brain and spinal cord tissue can be used as a positive control for this antibody.
The molecular weight of NEFH is 200 kDa.
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Characterization of neuronal populations in the human trigeminal ganglion and their association with latent herpes simplex virus-1 infection.
MA1-34345 was used in immunohistochemistry to study the association of human trigeminal ganglion neurons with latent HSV-1 infection
|Flowerdew SE,Wick D,Himmelein S,Horn AK,Sinicina I,Strupp M,Brandt T,Theil D,H?fner K||PloS one (8:null)||2013|
200 kDa neurofilament protein; neurofilament 200kDa; neurofilament heavy polypeptide; neurofilament triplet H protein; neurofilament, heavy polypeptide 200kDa; NF-H; NFH
mKIAA0845; NF-H; NF200; NFH