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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:3,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:300 | - |
Immunocytochemistry (ICC/IF) |
1:100 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Mouse / IgG2a |
Class |
Monoclonal |
Type |
Antibody |
Clone |
1C6D6 |
Immunogen |
NEIL1 Fusion Protein Ag8307 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1000 µg/mL |
Purification |
Protein A |
Storage buffer |
PBS with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Aliquoting is unnecessary for -20°C storage.
NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DNA endonuclease eight-like glycosylase 1; DNA glycosylase/AP lyase Neil1; DNA-(apurinic or apyrimidinic site) lyase Neil1; Endonuclease 8-like 1; endonuclease VIII; Endonuclease VIII-like 1; FLJ22402; FPG1; NEH1; nei endonuclease VIII-like 1; Nei homolog 1; nei-like DNA glycosylase 1; Nei-like protein 1
Gene Aliases: 2810450N13Rik; FPG1; hFPG1; NEI1; NEIL1
UniProt ID: (Human) Q96FI4, (Mouse) Q8K4Q6
Entrez Gene ID: (Human) 79661, (Mouse) 72774
Molecular Function:
DNA glycosylase
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