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Product Details
PA5-53351
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human NEU1. Recombinant protein control fragment (Product #RP-90540).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2644621
Product Specific Information
Immunogen sequence: GSVDTFRIPL ITATPRGTLL AFAEARKMSS SDEGAKFIAL RRSMDQGSTW SPTAFIVNDG DVPDGLNLGA VVSDVETGVV FLFYSLCAHK AGCQVASTML VWSKDDGVSW STPRNLSLDI GTEVF
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 86%.
Target Information
NEU1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A. Mutations in NEU1 gene can lead to sialidosis.The protein encoded by this gene encodes the lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acetylneuraminyl hydrolase; EC 3.2.1.18; exo-alpha-sialidase; FLJ93471; G9 sialidase; Lysosomal sialidase; N-acetyl-alpha-neuraminidase 1; sialidase 1 (lysosomal sialidase); Sialidase-1
Gene Aliases: NANH; NEU; NEU1; SIAL1
UniProt ID: (Human) Q99519
Entrez Gene ID: (Human) 4758
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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