Sequence of this protein is as follows: GQGGEAAHHT RSPYSTFYPP YHSPELTTPP GHGTLDNSKS MKPYNYCSAY ESFYESTSPE CASPQFEGPL SPPPINYNGI FSLKQEETLD YGKNYNYGMH
NEUROD6 contains 1 basic helix-loop-helix (bHLH) domain. It activates E box-dependent transcription in collaboration with TCF3/E47 and may be a trans-acting factor involved in the development and maintenance of the mammalian nervous system. It transactivates the promoter of its own gene.
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Protein Aliases: bHLHa2; brain my051 protein; Class A basic helix-loop-helix protein 2; NeuroD6; Neurogenic differentiation factor 6; Protein atonal homolog 2
Gene Aliases: ATOH2; BHLHA2; Math-2; MATH2; My051; NEUROD6; Nex1; NEX1M
UniProt ID: (Human) Q96NK8
Entrez Gene ID: (Human) 63974
Molecular Function: basic helix-loop-helix transcription factor