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NeoBiotechnologies
Positive Control: colon HeLa cells. Human fetal gut liver or heart.
Cellular Location: Nucleus.
Neurog 3 protein contains one basic helix-loop-helix (bHLH) domain.It is both necessary and sufficient to induce endocrine islet cell differentiation from embryonic pancreatic progenitors. Not only does itinitiates endocrine cell differentiation, italso promotes islet cell maturation and maintains islet function. It is reported that Neurogenin 3 can redirect the differentiation of bipotential secretory progenitors to endocrine rather than goblet cell fate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: bHLHa7; Class A basic helix-loop-helix protein 7; Neurogenin-3; neurogenin3; NGN-3; Protein atonal homolog 5
Gene Aliases: ATOH5; BHLHA7; Math4B; NEUROG3; NGN-3; NGN3
UniProt ID: (Human) Q9Y4Z2
Entrez Gene ID: (Human) 50674
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