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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues 871-888 of human NFBD1.|
|Storage buffer||PBS with 0.2% gelatin|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:200-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Suggested positive control: Jurkat whole cell lysate.
NFBD1, nuclear factor with BRCT domains protein 1, participates in the early response to DNA damage. It is thought to be a member of the BRCT (BRCA1 C-terminus) superfamily of nuclear proteins. It contains an N-terminus forkhead-associated (FHA) motif, two C-terminus BRCT motifs and 13 internal repetitions of a 41 amino acid sequence. A more recent renaming of NFBD1 is MDC1 (mediator of DNA damage checkpoint protein).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
DAAP-285E11.7; DKFZp781A0122; homologue to Drosophila photoreceptor protein calphotin; KIAA0170; mediator of DNA-damage checkpoint 1; MGC166888; NFBD1; nuclear factor with BRCT domains 1
KIAA0170; MDC1; NFBD1