ABS 043-10-02 binds free NGAL in mouse serum.
ABS 043-10-02 may be used in Western blot and sandwich ELISA with ABS 043-29-02. It is recommended to use ABS 043-10-02 as the capture antibody, and biotinylated ABS 043-29B-S as the detection antibody.
The ABS 043-10-02 immunogen is recombinant mouse NGAL adsorbed onto aluminum hydroxide gel.
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
NGAL (Neutrophil gelatinase-associated lipocalin, lipocalin 2, siderocalin and neutrophil lipocalin) is a 25 kDa glycosylated single chain monomer and member of the lipocalin family of proteins that bind and transport small lipophilic molecules. NGAL is released by activated neutrophils, can form dimers and small amounts of higher oligomers, and complexes with matrix metalloproteinase 9 (MMP-9, gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by ischemic or nephrotoxic kidney injury.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 24p3; HGNC:6526; Lipocalin-2; Lipocalin2; Neutrophil gelatinase-associated lipocalin; NGAL; Oncogene 24p3; OTTHUMP00000022240; p25; RP23-161B9.11; secreted inducible protein 24; Siderocalin LCN2; SV-40-induced 24P3 protein; uterocalin
Gene Aliases: 24p3; AW212229; Lcn2; Sip24
UniProt ID: (Mouse) P11672
Entrez Gene ID: (Mouse) 16819