This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
MA5-13314 targets Neurotrophin Receptor /NGF-Receptor (p75NGFR) in FACS, ICC/IF and WB applications and shows reactivity with Feline, Ferret, Human, Rat, Non-human primate, and Rabbit samples. This antibody does not react with rat tissue in Western blot applications.
The MA5-13314 immunogen is nGFR from A875 melanoma cells.
Neurotrophic factors control the survival, differentiation and maintenance of neurons in the peripheral and central nervous systems, and of other neural crest-derived cell types. Developing sympathetic neurons are absolutely dependent upon nerve growth factor (NGF) during the period of target competition in vivo. Antibodies reacting specifically with NGFR p75 are useful tools in the detection and characterization of NGFR p75, to enhance our understanding of a wide range of phenomena in the development, plasticity and repair of the nervous system.
Protein Aliases: CD271; CD271 antigen; Gp80-LNGFR; low affinity nerve growth factor receptor; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; nerve growth factor receptor (TNFR superfamily, member 16); nerve growth factor receptor, fast; NGF receptor; p-75; p75 ICD; p75 ntr; TNFR superfamily, member 16; TNR16; Tumor necrosis factor receptor superfamily member 16
Gene Aliases: CD271; Gp80-LNGFR; LNGFR; NGFR; p75; p75(NTR); p75NTR; RNNGFRR; TNFRSF16