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Invitrogen
This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:10-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:10-1:200 | View 1 publication 1 publication |
Flow Cytometry (Flow) |
Assay-dependent | View 2 publications 2 publications |
Immunohistochemistry (IHC) |
- | View 11 publications 11 publications |
Immunoprecipitation (IP) |
- | View 1 publication 1 publication |
Product Specifications | |
---|---|
Species Reactivity |
Cat, Ferret, Human, Non-human primate, Rabbit, Rat |
Published species |
Human, Mouse, Rat |
Host/Isotype |
Mouse / IgG1, kappa |
Class |
Monoclonal |
Type |
Antibody |
Clone |
NGFR5 |
Immunogen |
NGFR from A875 melanoma cells |
Conjugate |
Biotin
|
Form |
Liquid |
Concentration |
0.2 mg/mL |
Purification |
Protein G |
Storage buffer |
PBS, pH 7.4, with 0.2% BSA |
Contains |
0.09% sodium azide |
Storage conditions |
4° C |
RRID |
AB_10982271 |
MA5-13311 targets Neurotrophin Receptor /NGF-Receptor (p75NGFR) in FACS, WB and ICC/IF applications and shows reactivity with Feline, Ferret, Human, Non-human primate, Rat and Rabbit samples.
The MA5-13311 immunogen is nGFR from A875 melanoma cells.
Neurotrophic factors control the survival, differentiation and maintenance of neurons in the peripheral and central nervous systems, and of other neural crest-derived cell types. Developing sympathetic neurons are absolutely dependent upon nerve growth factor (NGF) during the period of target competition in vivo. Antibodies reacting specifically with NGFR p75 are useful tools in the detection and characterization of NGFR p75, to enhance our understanding of a wide range of phenomena in the development, plasticity and repair of the nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD271; CD271 antigen; Gp80-LNGFR; low affinity nerve growth factor receptor; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; nerve growth factor receptor (TNFR superfamily, member 16); nerve growth factor receptor, fast; NGF receptor; p-75; p75 ICD; p75 ntr; TNFR superfamily, member 16; TNR16; Tumor necrosis factor receptor superfamily member 16
Gene Aliases: CD271; Gp80-LNGFR; LNGFR; NGFR; p75; p75(NTR); p75NTR; RNNGFRR; TNFRSF16
UniProt ID: (Human) P08138, (Rat) P07174
Entrez Gene ID: (Human) 4804, (Rabbit) 100349095, (Rat) 24596
Molecular Function:
transmembrane signal receptor
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