MA5-13311 targets Neurotrophin Receptor /NGF-Receptor (p75NGFR) in FACS, WB and ICC/IF applications and shows reactivity with Feline, Ferret, Human, Non-human primate, Rat and Rabbit samples.
The MA5-13311 immunogen is nGFR from A875 melanoma cells.
NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR).
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Protein Aliases: CD271; Gp80-LNGFR; LNGFR; low affinity nerve growth factor receptor; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; nerve growth factor receptor (TNFR superfamily, member 16); nerve growth factor receptor, fast; NGF receptor; p-75; p75 ICD; p75NTR; RNNGFRR; TNFR superfamily, member 16; Tumor necrosis factor receptor superfamily member 16
Gene Aliases: CD271; Gp80-LNGFR; LNGFR; NGFR; p75; p75(NTR); p75NTR; RNNGFRR; TNFRSF16