MA5-13314 targets Neurotrophin Receptor /NGF-Receptor (p75NGFR) in FACS, ICC/IF and WB applications and shows reactivity with Feline, Ferret, Human, Rat, Non-human primate, and Rabbit samples. This antibody does not react with rat tissue in Western blot applications.
The MA5-13314 immunogen is nGFR from A875 melanoma cells.
NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR).
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Protein Aliases: CD271; Gp80-LNGFR; LNGFR; low affinity nerve growth factor receptor; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p-75; p75 ICD; p75NTR; RNNGFRR; TNFR superfamily, member 16; Tumor necrosis factor receptor superfamily member 16
Gene Aliases: CD271; Gp80-LNGFR; NGFR; p75(NTR); p75NTR; TNFRSF16
UniProt ID: (Human) P08138
Entrez Gene ID: (Human) 4804