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|Tested species reactivity||Dog, Cat, Human, Sheep, Pig, Rabbit|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Human WM245 melanoma cells.|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||20 µg/ml|
|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (IHC)||2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 1 publications below|
MA1-18418 detects p75 NTR from human, cat, dog, pig, rabbit and ovine samples. This antibody does not cross-react with rat and mouse p75 NTR.
MA1-18418 has been successfully used in immunohistochemistry, immunofluorescence, ELISA and flow cytometry applications.
The MA1-18418 immunogen is human WM245 melanoma cells.
For long term storage, glycerol (1:1) may be added for additional stability.
Reconstitute with 100 ul of distilled water.
Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Functional sphere profiling reveals the complexity of neuroblastoma tumor-initiating cell model.
MA1-18418 was used in immunohistochemistry to study the cancer stem cell model of neuroblastoma initiation
|Coulon A,Flahaut M,Mühlethaler-Mottet A,Meier R,Liberman J,Balmas-Bourloud K,Nardou K,Yan P,Tercier S,Joseph JM,Sommer L,Gross N||Neoplasia (New York, N.Y.) (13:991)||2011|
CD271; LNGFR; low affinity nerve growth factor receptor; low affinity neurotrophin receptor p75NTR; low-affinity nerve growth factor receptor; nerve growth factor receptor; nerve growth factor receptor (TNFR superfamily, member 16); NGF receptor; p-75; p75 ICD; p75NTR; RNNGFRR; TNFR superfamily, member 16
CD271; Gp80-LNGFR; NGFR; p75(NTR); p75NTR; TNFRSF16