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|Tested species reactivity||Cat, Human, Pig|
|Published species reactivity||Pig, Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human melanoma cell line, WM245.|
|Contains||15mM sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay dependent|
|Flow Cytometry (Flow)||Assay dependent|
|Immunocytochemistry (ICC)||Assay dependent|
|Immunofluorescence (IF)||Assay dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay dependent|
|Immunoprecipitation (IP)||Assay dependent|
|Radioimmune Assays (RIA)||Assay-dependent|
|Western Blot (WB)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-20167 detects p75 NGF receptor in human, feline, and porcine samples. This antibody does not cross-react with mouse, rat, or chicken p75 NGF receptors.
MA1-20167 has been successfully used in ELISA, FACS, immunocytochemistry, immunofluorescence, immunohistochemistry (paraffin), immunoprecipitation, and Western blot procedures.
The MA1-20167 immunogen is human melanoma cell line, WM245. The epitope is known to be located within the third or fourth cystine-rich repeats of the NGFR molecule.
Neurotrophic factors control the survival, differentiation and maintenance of neurons in the peripheral and central nervous systems, and of other neural crest-derived cell types. Developing sympathetic neurons are absolutely dependent upon nerve growth factor (NGF) during the period of target competition in vivo. Antibodies reacting specifically with NGFR p75 are useful tools in the detection and characterization of NGFR p75, to enhance our understanding of a wide range of phenomena in the development, plasticity and repair of the nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Development of a functional schwann cell phenotype from autologous porcine bone marrow mononuclear cells for nerve repair.
MA1-20167 was used in immunocytochemistry to develop a quick and simple method for the generation of functional Schwann-like cells from autologous pig bone marrow mononuclear cells
|Rutten MJ,Janes MA,Chang IR,Gregory CR,Gregory KW||Stem cells international (2012:null)||2012|
Functional sphere profiling reveals the complexity of neuroblastoma tumor-initiating cell model.
MA1-20167 was used in immunohistochemistry to study the cancer stem cell model of neuroblastoma initiation
|Coulon A,Flahaut M,Mühlethaler-Mottet A,Meier R,Liberman J,Balmas-Bourloud K,Nardou K,Yan P,Tercier S,Joseph JM,Sommer L,Gross N||Neoplasia (New York, N.Y.) (13:991)||2011|
CD271; LNGFR; low affinity nerve growth factor receptor; low affinity neurotrophin receptor p75NTR; low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; p75NTR; RNNGFRR; TNFR superfamily, member 16
CD271; Gp80-LNGFR; NGFR; p75(NTR); p75NTR; TNFRSF16