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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Recombinant human p75.|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||20 µg/ml|
|Immunofluorescence (IF)||1-5 µg/ml|
|Immunohistochemistry (IHC)||1 - 2 µg/ml|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-18421 detects p75 NTR from human, mouse, and rat samples. Other species have not yet been tested but it is expected that this antibody will be useful for the study of p75 in primates and other species.
MA1-18421 has been successfully used in western blot, immunohistochemistry, immunofluorescence and flow cytometry applications.
The MA1-18421 immunogen is recombinant human p75.
This product is not suitable for denaturing western blot applications.
This product can be stored at 4C for up to four months with the addition of an appropriate antimicrobial agent.
Low affinity receptor that can bind NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CD271; gp80-LNGFR; LNGFR; low affinity nerve growth factor receptor; low affinity neurotrophin receptor p75NTR; low-affinity nerve growth factor receptor; nerve growth factor receptor (TNFR superfamily, member 16); nerve growth factor receptor, fast; NGF receptor; p75 ICD; p75 neurotrophin receptor; p75NTR; RNNGFRR; TNFR superfamily, member 16; tumor necrosis factor receptor superfamily member 16
CD271; Gp80-LNGFR; LNGFR; NGFR; p75; p75(NTR); p75NGFR; p75NTR; RNNGFRR; TNFRSF16