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Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha-ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle.
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Protein Aliases: epididymis secretory sperm binding protein Li 8a; Nit protein 2; nitrilase family, member 2; Nitrilase homolog 2; Omega-amidase NIT2
Gene Aliases: CUA002; HEL-S-8a; NIT2
UniProt ID: (Human) Q9NQR4
Entrez Gene ID: (Human) 56954
Molecular Function: hydrolase