Applications | Tested Dilution | Publications |
---|---|---|
Immunohistochemistry (Paraffin) (IHC (P)) |
1-2 µg/mL | - |
Peptide Array (Array) |
Assay-dependent | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Mouse / IgG2b, kappa |
Class |
Monoclonal |
Type |
Antibody |
Clone |
NKX3.1, 3350 |
Immunogen |
Recombinant fragment (around aa 92-224) of human NKX3.1 protein |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
200 µg/mL |
Purification |
Protein A |
Storage buffer |
PBS, pH 7.4, with 0.05% BSA |
Contains |
0.05% sodium azide |
Storage conditions |
4° C |
Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
The homeodomain-containing transcription factor NKX3-1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Homeobox protein NK-3 homolog A; Homeobox protein Nkx-3.1; NK homeobox, family 3, A; NK3 transcription factor homolog A; NK3 transcription factor related, locus 1; NKX3-1 antibody; prostate-specific ag
Gene Aliases: BAPX2; NKX3; NKX3-1; NKX3.1; NKX3A
UniProt ID: (Human) Q99801
Entrez Gene ID: (Human) 4824
Molecular Function:
homeodomain transcription factor
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