|Tested species reactivity||Rat|
|Published species reactivity||Not Applicable|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (KDAHEKDDFHHLS) corresponding to the internal amino acids of GRIN2B|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||2-4 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
This antibody is predicted to react with canine, human and mouse based on sequence homology.
N-methyl-D-aspartate receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 and NR3 . The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Parkin regulates kainate receptors by interacting with the GluK2 subunit.
PA5-18536 was used in western blot to elucidate how mutations in parkin result in autosomal recessive juvenile parkinsonism
|Maraschi A,Ciammola A,Folci A,Sassone F,Ronzitti G,Cappelletti G,Silani V,Sato S,Hattori N,Mazzanti M,Chieregatti E,Mulle C,Passafaro M,Sassone J||Nature communications (5:null)||2014|