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FIGURE: 1 / 2
NMUR2 (extracellular) Antibody (ANR-072-200UL) in ICC/IF
Expression of Neuromedin-U receptor 2 in rat C6 cells - Cell surface detection of NMUR2 in intact living rat brain glioma C6 cells. A. Extracellular staining of cells using Anti-NMUR2 (extracellular) Antibody (#ANR-072), (1:50), (red). DAPI is used as the counterstain (blue). B. Live view of the cells merged with NMUR2 staining.
Product Details
ANR-072-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)KLENASWIHDPLMK, corresponding to amino acid residues 3-16 of rat NMUR2, Extracellular, N-terminus
Conjugate
Form
Lyophilized
Concentration
0.85 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
This gene encodes a protein from the G-protein coupled receptor 1 family. This protein is a receptor for neuromedin U, which is a neuropeptide that is widely distributed in the gut and central nervous system. This receptor plays an important role in the regulation of food intake and body weight.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G-protein coupled receptor FM-4; G-protein coupled receptor TGR-1; G-protein-coupled receptor FM-4; growth hormone secretagogue receptor family, member 4; Neuromedin-U receptor 2; NMU-R2
Gene Aliases: FM-4; FM4; NMU-R2; NMU2R; NMUR2; TGR-1; TGR1
UniProt ID: (Human) Q9GZQ4, (Rat) Q9ESQ4, (Mouse) Q8BZ39
Entrez Gene ID: (Human) 56923, (Rat) 64042, (Mouse) 216749
reduction of food intake in response to dietary excess
calcium ion transport
regulation of smooth muscle contraction
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
cell-cell signaling
central nervous system development
grooming behavior
feeding behavior
calcium-mediated signaling
activation of phospholipase A2 activity by calcium-mediated signaling
inositol phosphate-mediated signaling
response to pain
arachidonic acid secretion
chloride transmembrane transport
chloride transport
chemical synaptic transmission
signal transduction
G-protein coupled receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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