Immunogen sequence: SSFMFWRNP LPNIDHELQE LLIDRGEDVP SEEEEEEENG FEDRKDDSDD DGGGWITPSN IKQIQQELEQ CDVPEDVRVG CLTTDFAMQN VLLQMGLHVL AVNGMLIREA RSYILRCHGC FKTTSDMSRV FCSHCGNKTL KKVSVTVSDD GTLHMHFSRN PKVLNPRGLR YSLPTPKGGK YAINPHLTED QRFPQLRLSQ KARQKTNVFA PDYIAGVSPF VENDISSRSA TLQVRDSTLG AGRRRLNPNA SRKKFVKKR (36-293 aa encoded by BC000050)
In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA.
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Protein Aliases: adenocarcinoma antigen recognized by T lymphocytes 4; nin one binding protein; NIN1/RPN12 binding protein 1 homolog; Phosphorylation regulatory protein HP-10; Protein ART-4; PSMD8 binding protein 1; RNA-binding protein NOB1
Gene Aliases: ART-4; ART4; MST158; MSTP158; NOB1; NOB1P; PSMD8BP1
UniProt ID: (Human) Q9ULX3
Entrez Gene ID: (Human) 28987