This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: ANP-C; ANPRC; Atrial natriuretic peptide C-type receptor; Atrial natriuretic peptide clearance receptor; Atrial natriuretic peptide receptor 3; Atrial natriuretic peptide receptor type C; atrionatriuretic peptide receptor C; guanylate cyclase C; natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C); NPR-C
Gene Aliases: ANP-C; ANPR-C; ANPRC; C5orf23; GUCY2B; NPR-C; NPR3; NPRC
UniProt ID: (Human) P17342
Entrez Gene ID: (Human) 4883