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NR2C2 Antibody (TA807250) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NR2C2 (RC219184, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-NR2C2. Positive lysates LY401137 (100 µg) and LC401137 (20 µg) can be purchased separately from OriGene.
Product Details
TA807250
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI1C4
Immunogen
Human recombinant protein fragment corresponding to amino acids 1-241 of human NR2C2 produced in E.coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Nuclear hormone receptor TR4; Nuclear receptor subfamily 2 group C member 2; nuclear receptor subfamily 2, group C, member 2; Orphan nuclear receptor TAK1; Orphan nuclear receptor TR4; orphan receptor TR4; testicular nuclear receptor 4; Testicular receptor 4; TR2R1
Gene Aliases: NR2C2; TAK1; TR4
UniProt ID: (Human) P49116
Entrez Gene ID: (Human) 7182
regulation of transcription, DNA-templated
transcription initiation from RNA polymerase II promoter
spermatogenesis
nervous system development
cerebellum development
cell differentiation
p38MAPK cascade
positive regulation of embryonic development
steroid hormone mediated signaling pathway
positive regulation of myoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of behavior
meiotic cell cycle
mitophagy in response to mitochondrial depolarization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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