This antibody is expected to recognize both reported isoforms (NP_004792.1 and NP_620072.1).
It is predicted to react with canine, mouse and rat based on sequence homology.
Neurexins function in the vertebrate nervous system as cell adhesion molecules and receptors. Two neurexin genes are among the largest known in human sequences and laminin G domains, and they interact with neurexophilins. Beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. The RefSeq Project has decided to create only a few representative transcript variants of the multitude that are possible.
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Protein Aliases: DKFZp313P2036; FLJ35941; Hs.22998; KIAA0578; neurexin 1; neurexin I; Neurexin I-alpha; Neurexin I-beta; Neurexin-1; Neurexin-1-alpha; Neurexin-1-beta; NRXN1
Gene Aliases: Hs.22998; KIAA0578; NRXN1; PTHSL2; SCZD17
UniProt ID: (Human) Q5HYI0
Entrez Gene ID: (Human) 9378
Molecular Function: apolipoprotein cell adhesion molecule enzyme modulator extracellular matrix protein hydrolase membrane-bound signaling molecule metalloprotease oxidase oxidoreductase protease receptor serine protease signaling molecule transfer/carrier protein transporter