|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:200|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide, KLH conjugated.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.7|
|Contains||0.01% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
PA1-32696 detects NTR2 from human samples.
PA1-32696 has been successfully used in immunohistochemistry (paraffin tissue) applications.
The PA1-32696 immunogen is a synthetic peptide, KLH conjugated.
Store at 4°C short term. For extended storage, aliquot and store at -20°C, avoiding freeze/thaw cycles.
The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Levocabastine-sensitive neurotensin receptor; Neurotensin receptor type 2; neurotensin receptor, type 2; NT-R-2
Gene Aliases: NTR2; NTSR2
UniProt ID: (Human) O95665
Entrez Gene ID: (Human) 23620
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