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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant extracellular fragment of human NTRK3 (aa32-429) fused with hIgGFc tag expressed in HEK293 cells.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-15548 targets NTRK3 in WB applications and shows reactivity with Human samples.
The MA5-15548 immunogen is purified recombinant extracellular fragment of human NTRK3 (aa32-429) fused with hIgGFc tag expressed in HEK293 cells.
MA5-15548 detects NTRK3 which has a predicted molecular weight of approximately 94kDa.
This gene encodes a member of the neurotrophic tyrosine receptor kinase family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; ETV6-NTRK3 fusion; gp145(trkC); neurotrophic tyrosine kinase, receptor, type 3; NTRK3; TRKC; tyrosine kinase receptor C
gp145(trkC); GP145-TrkC; NTRK3; TRKC