Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. This protein binds and stabilizes cytoplasmic mRNA and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. It regulates the transcription of numerous genes and promotes separation of DNA strands that contain mismatches or are modified by cisplatin. It has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro), and it may play a role in DNA repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adenosine diphosphoribose pyrophosphatase; ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ADP-ribose pyrophosphatase, mitochondrial; ADP-ribose pyrosphosphatase NUDT9; ADPR-PPase; nucleoside diphosphate linked moiety X-type motif 9; Nucleoside diphosphate-linked moiety X motif 9; nudix (nucleoside diphosphate linked moiety X)-type motif 9; Nudix motif 9
Gene Aliases: NUDT10; NUDT9; PSEC0099; UNQ3012/PRO9771
UniProt ID: (Human) Q9BW91
Entrez Gene ID: (Human) 53343
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support