|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to amino acids 881-930 of human NY-CO-1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.2|
|Contains||15mM sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:200|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody detects endogenous protein at a molecular weight of 110 kDa.
Purity is >95% by SDS-PAGE.
Nuclear export mediator factor, NEMF, plays a role in nuclear export. It is expressed in brain, heart, liver, lung, spleen, and skeletal muscle tissue, and expressed at lower levels in stomach and testis. It interacts (via its N-terminus) with XPO1; the N-terminal domain contains a nuclear export signal and the C-terminal domain may interact with cargo proteins. This protein is active in normal lung tissue but is inactive in several lung cancer cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.