|Tested species reactivity||Not Applicable|
|Host / Isotype||E.coli|
|Storage buffer||0.05M tris HCl, pH 7.5, with 0.01M L-glutathione|
|Storage Conditions||-20°C or -80°C if preferred|
|Tested Applications||Dilution *|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This product is a recombinant protein corresponding to full-length human NY-ESO-1.
On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 49kDa.
NY-ESO-1, a member of the CT(cancer/testies) family, is a tumor specific shared antigen with distinctive immunogenicity. The molecular basis of T cell-mediated antitumor immunity has been elucidated by the identification of a number of tumor antigens recognized by CD8+ T cells. Among these antigens, NY-ESO-1 is of particular interest because both the cytotoxic T lymphocyte and antibody have been shown to react with this antigen. The NY-ESO-1 has been detected in normal testis and in a range of human tumor types. NY-ESO-1 reactivity in testis is restricted germ cells, particularly in the spermatogonia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.