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Search Thermo Fisher Scientific
Invitrogen
This antibody binds to the alpha 4 binds subunit of alpha 4 Beta 1 (also known as very late antigen 4 [VLA-4] or CD49d-CD29) and alpha 4 Beta 7 integrin
Natalizumab is a recombinant, humanized monoclonal antibody, binds to alpha4beta1-integrinand blocks its interaction with vascular cell adhesion molecule-1 (VCAM-1). Natalizumab can be used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease. Natalizumab is also the first targeted therapy which blocks an essential mechanism for lymphocyte entry to the CNS and thus prevents acute demyelinating relapses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AN 100226; BG00002
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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