|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgM|
|Immunogen||Synthetic peptide corresponding to a portion of the extracellular domain of Nav1.5.|
|Storage buffer||PBS, pH 7.2|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunocytochemistry (ICC)||10 µg/ml|
|Immunofluorescence (IF)||10 ug/ml|
|Western Blot (WB)||2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-27429 detects Nav 1.5 from human samples.
MA1-27429 may be successfully used in immunocytochemistry, immunofluorescence and Western blot applications.
The MA1-27429 immunogen is a synthetic peptide corresponding to an extracellular domain of Nav1.5.
Voltage-gated sodium channesl (VGSCs) mediate regenerative cell membrane depolarization and conduction of electrical signalling in nerves and muscles. Expression is also detected in lymphocytes, glia, and fibroblasts. VGSC proteins are comprised of a core
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