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|Tested species reactivity||Human, Mouse, Rat, Avian|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Native mouse beta NGF purified from submaxillary salivary gland.|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|ELISA (ELISA)||1-3 µg/ml|
|Inhibition Assays (IA)||1-3 µg/ml|
|Immunohistochemistry (IHC)||1-3 µg/ml|
|Western Blot (WB)||1-3 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-18377 detects beta NGF from human, mouse, rat, and avian samples. This antibody does not react with bovine protein. A cross reactivity of less than 1% to recombinant human BDNF, NT3, NT4/5 by ELISA has been shown.
PA1-18377 has been successfully used in immunohistochemistry, ELISA, Western blot, and inhibition assay procedures.
The PA1-18377 immunogen is native mouse beta NGF purified from submaxillary salivary gland.
Reconstitute with 500 ul of distilled water. Glycerol (1:1) may be added for additional stability.
This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
beta Nerve Growth Factor; beta-nerve growth factor; beta-NGF; nerve growth factor (beta polypeptide); nerve growth factor, beta; nerve growth factor, beta subunit
Beta-NGF; HSAN5; NGF; NGFB