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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human Neurod (amino acids: 26-91) expressed in E. Coli.|
|Storage buffer||PBS with 0.5% proprietary stabilizer|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500 - 1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-17137 targets NeuroD in pep-ELISA and WB applications and shows reactivity with Human and Mouse samples.
The MA5-17137 immunogen is purified recombinant fragment of human Neurod (amino acids: 26-91) expressed in E. Coli.
MA5-17137 detects NeuroD which has a predicted molecular weight of approximately 40kDa.
This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
basic helix-loop-helix transcription factor; beta-cell E-box transactivator 2; Beta-cell E-box transcriptional activator 2; Beta2; bHLHa3; Class A basic helix-loop-helix protein 3; NeuroD; NeuroD1; Neurogenic differentiation factor 1; neurogenic helix-loop-helix protein NEUROD
BETA2; BHF-1; BHLHA3; MODY6; NEUROD; NEUROD1