A suggested positive control is mouse small intestine tissue lysate.
PA5-34472 can be used with blocking peptide PEP-1514.
Neurogenin-2 (NGN2) is a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells and is expressed in neural progenitor cells within the developing central and peripheral nervous systems. NGN2 is thought to work with Nurr1 to play a role in the differentiation and survival of midbrain dopaminergic neurons. It has also been suggested for use in human embryonic neural progenitors as a graft for spinal cord injuries
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Protein Aliases: atoh4; atonal homolog 4; basic helix-loop-helix protein 8; bHLHa8; Class A basic helix-loop-helix protein 8; Helix-loop-helix protein mATH-4A; mATH4A; Neurog2; neurogenin 2; Neurogenin-2; NGN-2; NGN2; Protein atonal homolog 4
Gene Aliases: Ath4a; ATOH4; BHLHA8; Math4A; NEUROG2; ngn-2; NGN2