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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues S P E K A K S P E K A K S, which is a repeated motif of human NFH.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-4133 detects heavy neurofilament subunit tail in human samples.
PA1-4133 has been successfully used in Western blot procedures.
The PA1-4133 immunogen is a synthetic peptide corresponding to residues S P E K A K S P E K A K S, which is a repeated motif of human NFH.
The human heavy neurofilament subunit (NFH) tail that contains a repeated motif, XKSPYK. Deletions in this repeat region are strongly implicated as a primary event in amyotrophic lateral sclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
200 kDa neurofilament protein; KIAA0845; neurofilament triplet H protein; neurofilament, heavy polypeptide 200kDa; NF-H; NFH; NHC
CMT2CC; KIAA0845; NEFH; NFH