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|Tested species reactivity||Human, Non-human primate|
|Published species reactivity||Sheep|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues 350-400 of human NPY2-R.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 0.2% gelatin|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||10 µg/ml|
|Western Blot (WB)||1-3 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (Paraffin) (IHC (P))||See 1 publications below|
NPY2R is also expected to react with mouse and canine samples based on sequence homology.
Suggested positive control: human kidney protein, kidney lysate.
NPY2 receptor is a member of GPCR1 family and is localized primarily on Neuropeptide Y-expressing neurons in the hypothalamic region of the brain. It binds specifically to the C-terminal of Neuropeptide Y and is responsible for regulation of presynaptic relase of noradrenaline. Reports suggest a probable role of NPY2 receptor in regulation of feeding behavior, energy homeostasis and also in regulating cardiovascular system. Variations in the NPY2 receptor genes have been linked to occurrence of Diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Immunohistochemical evaluation of the goat forestomach during prenatal development.
PA1-41576 was used in immunohistochemistry - paraffin section to evaluate markers of neuroendocrine cells, glial cells and peptidergic innervations during prenatal development.
|Garcia A,Masot J,Franco A,Gazquez A,Redondo E||Journal of veterinary science (15:35)||2014|