|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 606 and 828 of Human Neuropilin 1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27714 targets Neuropilin 1 in WB applications and shows reactivity with Human samples.
The PA5-27714 immunogen is recombinant fragment corresponding to a region within amino acids 606 and 828 of Human Neuropilin 1.
NRP1 is a membrane-bound coreceptor to a tyrosine kinase receptor for both vascular endothelial growth factor (VEGF; MIM 192240) and semaphorin (see SEMA3A; MIM 603961) family members. NRP1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BDCA4; CD304; Neuropilin-1; NRP; transmembrane receptor; Vascular endothelial cell growth factor 165 receptor; VEGF165R
Gene Aliases: BDCA4; CD304; NP1; NRP; NRP1; VEGF165R
UniProt ID: (Human) O14786
Entrez Gene ID: (Human) 8829
Molecular Function: apolipoprotein cell adhesion molecule enzyme modulator extracellular matrix protein hydrolase membrane-bound signaling molecule metalloprotease oxidase oxidoreductase protease receptor serine protease signaling molecule transfer/carrier protein transporter
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