MA1-10608 detects Neutrophil elastase from human samples.
MA1-10608 has been successfully used in ELISA and in studies of inhibition and enzyme kinetics of neutrophil elastase.
The MA1-10608 immunogen is purified human Neutrophil Elastase.
The neutrophil form of elastase is 218 amino acids long, with two asparagine-linked carbohydrate chains (see glycosylation). It is present in azurophil granules in the neutrophil cytoplasm. There appear to be two forms of neutrophil elastase, termed IIa and IIb.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Bone marrow serine protease; ELA2A; Elastase; elastase 2, neutrophil; Elastase-2; Elastase2; granulocyte-derived elastase; HLE; Human leukocyte elastase; leukocyte elastase; Medullasin; Neutrophil elastase; PMN elastase; polymorphonuclear elastase
Gene Aliases: ELA2; ELANE; GE; HLE; HNE; NE; PMN-E; SCN1
UniProt ID: (Human) P08246
Entrez Gene ID: (Human) 1991
Molecular Function: serine protease