|Tested species reactivity||Human, Mouse|
|Host / Isotype||Mouse / IgG1, kappa|
|Storage buffer||tris glycine with 0.15M NaCl|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1 µg/10^6 cells|
|Immunohistochemistry (Frozen) (IHC (F))||Assay-Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||1:200-1:500|
|Western Blot (WB)||1:500-1:1500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Suggested positive control: whole Alzheimer's Disease brain lysate.
Nitrated alpha Synuclein may be involved in the regulation of dopamine release and transport. It is a soluble protein which is primarily localized at the presynaptic regions of axons. It can form filamentous aggregates, which are the major non amyloid component of intracellular inclusions in many neurodegenerative synucleinopathies. Nitrated alpha Synuclein has been found to reduce neuronal responsiveness to several apoptotic stimuli which leads to a decreased caspase-3 activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.