The antibody detects endogenous levels of total NKX2-6 protein.
This gene encodes a homeobox-containing protein that belongs to the NK-2 homeobox family. This protein is a vertebrate homolog of Drosophila homeobox-containing protein called 'tinman', which has been shown to be essential for development of the heart-like dorsal vessel. In conjunction with related gene, NKX2-5, this gene may play a role in both pharyngeal and cardiac embryonic development. Mutations in this gene are associated with persistent truncus arteriosus.[provided by RefSeq, Aug 2011].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Homeobox protein NK-2 homolog F; homeobox protein NK2 homolog F; Homeobox protein Nkx-2.6; homeobox protein NKX2.6; NK2 transcription factor related, locus 6; NKX2F; tinman paralog
Gene Aliases: CSX2; CTHM; NKX2-6; NKX2F; NKX4-2
UniProt ID: (Human) A6NCS4
Entrez Gene ID: (Human) 137814