The homeodomain-containing transcription factor NKX3-1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.
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Protein Aliases: Drosophila NK-3 transcription factor, locus 1; Homeobox protein NK-3 homolog A; Homeobox protein Nkx-3.1; NK homeobox, family 3, A; NK3 transcription factor homolog A; NK3 transcription factor related, locus 1; NKX3-1 antibody; prostate-specific ag
Gene Aliases: bagpipe; BAPX2; Bax; Nkx-3.1; NKX3; NKX3-1; NKX3.1; NKX3A
Molecular Function: homeodomain transcription factor