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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 17 amino acid peptide from internal region of human NR4A3.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||10 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
In IHC applications, antigen retrieval using Proteinase K treatment is recommended.
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Bovine, Dog, Elephant, Panda, Rabbit, Pig, Platypus (100%).
NOR-1, a NR4 nerve growth factor-like receptor, has been shown to affect neuronal development, T-cell apoptosis, and cancer development. NOR-1 binds to NBRE (NGFI-B response element) and regulates the pro-opiomelanocortin (POMC) gene. NOR-1 is induced rapidly but transiently by a variety of stimuli. Downregulation of NOR-1 and other NGFI-B family members is correlated with drug addiction-prone behavior of Lewis rats. Three human protein isoforms have been documented: NOR-1, NOR-1beta, and NOR-1 3' variant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CHN; chondrosarcoma, extraskeletal myxoid, fused to EWS; CSMF; MINOR; mitogen-induced nuclear orphan receptor; Neuron-derived orphan receptor; neuron-derived orphan receptor 1; Nor-1; NOR1; NR4A3; nuclear hormone receptor NOR-1; nuclear receptor subfamily 4, group A, member 3; Orphan receptor nor1; TEC receptor; translocated in extraskeletal chondrosarcoma
CHN; CSMF; MINOR; NOR1; NR4A3; TEC