|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (KAKKNLEVKKNN) corresponding to the internal amino acids of Npy2r|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||0.1-0.3 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with canine based on sequence homology.
NPY2 receptor is a member of GPCR1 family and is localized primarily on Neuropeptide Y-expressing neurons in the hypothalamic region of the brain. It binds specifically to the C-terminal of Neuropeptide Y and is responsible for regulation of presynaptic relase of noradrenaline. Reports suggest a probable role of NPY2 receptor in regulation of feeding behavior, energy homeostasis and also in regulating cardiovascular system. Variations in the NPY2 receptor genes have been linked to occurrence of Diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.