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|Tested species reactivity||Human|
|Published species reactivity||Rabbit, Human|
|Host / Isotype||Mouse / IgM|
|Immunogen||Colon carcinoma cell line Ls-174T.|
|Contains||0.05% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay dependent|
|Immunohistochemistry (Frozen) (IHC (F))||Assay dependent|
|Western Blot (WB)||Assay dependent.|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
NuMA (nuclear mitotic apparatus) is a long coil-coiled protein that plays a role in the interphase and mitosis phases of a cell cycle. In interphase, it has been hypothesized to play a structural role in the nucleoskeleton that may be important in nuclear organization and functions. During mitosis, it is associated with spindle microtubule organization and chromosome positioning. Therefore, this antibody is useful as a cell cycle marker.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Differential functional interplay of TOGp/XMAP215 and the KinI kinesin MCAK during interphase and mitosis.
MA1-35739 was used in immunocytochemistry to study the functional interplay between TOGp and the kinl kinesin MCAK in human leukemia cells
|Holmfeldt P,Stenmark S,Gullberg M||The EMBO journal (23:627)||2004|
Immunological relatedness of the sarcoplasmic reticulum Ca(2+)-ATPase and the Na+,K(+)-ATPase.
MA1-35739 was used in western blot to investigate the functional properties of three anti-calcium ATPase antibodies
|Molnar E,Varga S,Jona I,Seidler NW,Martonosi A||Biochimica et biophysica acta (1103:281)||1992|
centrophilin stabilizes mitotic spindle in mitotic cells; nuclear matrix protein-22; NUMA; SP-H antigen; structural nuclear protein
NMP-22; NMP22; NUMA; NUMA1