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Invitrogen
OCT1 (POU2F1) Recombinant Rabbit Monoclonal Antibody (JG62-35)
Product Details
MA5-41265
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Expression System |
HEK293 cells |
Class |
Recombinant Monoclonal |
Type |
Antibody |
Clone |
JG62-35 |
Immunogen |
Recombinant protein within N-terminal Human Oct-1 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein A |
Storage buffer |
TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
Contains |
0.05% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2899018 |
Target Information
OCT1 (POU2F1) is a ubiquitously expressed transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. It modulates transcription transactivation by NR3C1, AR and PGR (By similarity). In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: NF-A1; Oct-1; Octamer-binding protein 1; Octamer-binding transcription factor 1; Octamer-binding transcription factor-1; OTF-1; POU domain, class 2, transcription factor 1; ubiquitous transcription factor
Gene Aliases: 2810482H01Rik; NF-A1; Oct-1; oct-1B; OCT1; Otf-1; OTF1; POU2F1
UniProt ID: (Human) P14859, (Rat) P31503, (Mouse) P25425
Entrez Gene ID: (Human) 5451, (Rat) 171068, (Mouse) 18986
snRNA transcription from RNA polymerase II promoter
negative regulation of transcription, DNA-templated
liver regeneration
transcription, DNA-templated
olfactory placode formation
positive regulation of transcription from RNA polymerase II promoter
lens induction in camera-type eye
regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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