|Tested species reactivity||Human|
|Host / Isotype||Rat / IgG2b|
|Immunogen||ORC3 (hsORC) produced in P3-x63Ag.8.653 cells|
|Contains||0.1% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-17024 reacts with ORC3 in human samples.
MA5-17024 has been successfully used in immunoprecipitation and Western blot applications.
The MA5-17024 immunogen is ORC3 (hsORC) produced in P3-x63Ag.8.653 cells.
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. ORC3 is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.