Reconstitute with 150 µL of distilled water.\r
The peptide is homologous in mouse
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: APG4 (ATG4) autophagy-related homolog A; APG4 autophagy 4 homolog A; ATG4 autophagy related 4 homolog A; AUT-like 2 cysteine endopeptidase; AUT-like 2, cysteine endopeptidase; autophagin 2; Autophagin-2; autophagy 4 homolog A; autophagy related 4A, cysteine peptidase; autophagy-related 4A; Autophagy-related cysteine endopeptidase 2; Autophagy-related protein 4 homolog A; cysteine protease APG4A; Cysteine protease ATG4A; hAPG4A; MGC107179
Gene Aliases: AI627006; APG4A; ATG4A; Atg4al; AUTL2; AV169859
Molecular Function: hydrolase