Product is supplied at 1 mL (100 µL/mL).
Recently, a novel member of the leukocyte receptor complex (LRC) encoded family has been identified that is expressed specifically in osteoclast (OC). This protein names OC-associated receptor or OSCAR, play critical roles in the regulation of both innate and adaptive immune responses and bone-specific regulator of OC differentiation. Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This protein family plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: MGC33613; Ocl178; Osteoclast-associated immunoglobulin-like receptor; Osteoclast-associated receptor; osteoclast-associated receptor OSCAR; PIGR3
Gene Aliases: mOSCAR; mOSCAR-M1; mOSCAR-M2; mOSCAR-M3; Oscar
UniProt ID: (Mouse) Q8VBT3
Entrez Gene ID: (Mouse) 232790