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Product Details
CF503002
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:150 | - |
Flow Cytometry (Flow) |
1:100 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Dog, Human, Mouse, Rat |
Host/Isotype |
Mouse / IgG2a |
Class |
Monoclonal |
Type |
Antibody |
Clone |
OTI9E3 |
Immunogen |
Human recombinant protein fragment corresponding to amino acids 1-335 of human OSGEP produced in E.coli. |
Conjugate |
Unconjugated |
Form |
lyophilized |
Concentration |
1 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 8% trehalose |
Contains |
no preservative |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
Osgep (O-sialoglycoprotein endopeptidase), also known as GCPL1, is a 335 amino acid protein that is a member of the peptidase M22 family. Osgep specifically cleaves the 31-Arg-l-Asp-32 bond in glycophorin A, but it does not cleave desialylated glycoproteins, unglycosylated proteins or glycoproteins that are only N-glycosylated. Though ubiquitously expressed at low levels, highest levels of Osgep are found in liver, skeletal muscle and kidney. OSGEPL1, also known as Qri7, is a 414 amino acid protein that belongs to the KAE1/YgjD family and exists as three alternatively spliced isoforms. In tRNAs that have codons beginning with adenine, OSGEPL1 is required for the formation of a threonylcarbamoyl group on adenosine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hOSGEP; mOsgep; N6-L-threonylcarbamoyladenine synthase; O-sialoglycoprotease; O-sialoglycoprotein endopeptidase; O-sialoglycoprotein endopeptidase {ECO:0000255|HAMAP-Rule:MF_03180}; OSGEP; pasteurella haemolytica metalloprotease homolog with glycoprotein substrates/gpc-like protein 1; probable O-sialoglycoprotein endopeptidase; probable tRNA N6-adenosine threonylcarbamoyltransferase; probable tRNA N6-adenosine threonylcarbamoyltransferase {ECO:0000255|HAMAP-Rule:MF_03180}; probable tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP; Prsmg1/Gcpl1; t(6)A synthase; t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP; t(6)A37 threonylcarbamoyladenosine biosynthesis protein Osgep {ECO:0000255|HAMAP-Rule:MF_03180}; tRNA N6-adenosine threonylcarbamoyltransferase; tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP; tRNA threonylcarbamoyladenosine biosynthesis protein Osgep {ECO:0000255|HAMAP-Rule:MF_03180}
Gene Aliases: 1500019L24Rik; GCPL-1; GCPL1; KAE1; OSGEP; OSGEP1; PRSMG1
UniProt ID: (Human) Q9NPF4, (Rat) Q9WVS2, (Mouse) Q8BWU5
Entrez Gene ID: (Human) 55644, (Dog) 100687555, (Rat) 290028, (Mouse) 66246
Molecular Function:
RNA processing factor
metal ion binding
N(6)-L-threonylcarbamoyladenine synthase
transferase activity, transferring acyl groups other than amino-acyl groups
dihydrolipoamide branched chain acyltransferase activity
sterol O-acyltransferase activity
N-acetyltransferase activity
O-acyltransferase activity
palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity
carnitine O-acyltransferase activity
acetyltransferase activity
C-acyltransferase activity
palmitoyltransferase activity
N-acyltransferase activity
acylglycerol O-acyltransferase activity
serine O-acyltransferase activity
O-acetyltransferase activity
O-octanoyltransferase activity
octanoyltransferase activity
O-palmitoyltransferase activity
S-acyltransferase activity
S-acetyltransferase activity
S-malonyltransferase activity
malonyltransferase activity
C-palmitoyltransferase activity
transferase activity
transferase activity, transferring acyl groups
succinyltransferase activity
N-succinyltransferase activity
O-succinyltransferase activity
S-succinyltransferase activity
sinapoyltransferase activity
O-sinapoyltransferase activity
peptidyl-lysine N6-myristoyltransferase activity
peptidyl-lysine N6-palmitoyltransferase activity
benzoyl acetate-CoA thiolase activity
3-hydroxybutyryl-CoA thiolase activity
3-ketopimelyl-CoA thiolase activity
N-palmitoyltransferase activity
myristoyltransferase activity
acyl-CoA N-acyltransferase activity
protein-cysteine S-myristoyltransferase activity
protein-cysteine S-acyltransferase activity
dihydrolipoamide S-acyltransferase activity
glucosaminyl-phosphotidylinositol O-acyltransferase activity
ergosterol O-acyltransferase activity
lanosterol O-acyltransferase activity
naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity
2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity
2-methylhexanoyl-CoA C-acetyltransferase activity
butyryl-CoA 2-C-propionyltransferase activity
2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity
L-2-aminoadipate N-acetyltransferase activity
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity
keto acid formate lyase activity
Ras palmitoyltransferase activity
azetidine-2-carboxylic acid acetyltransferase activity
peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
acetyl-CoA:L-lysine N6-acetyltransferase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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