Reconstitute with 100 µL of distilled water.\r
The peptide is homologous in mouse.
Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA. Required for normal cell adhesion and cell migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: human T-lymphoma invasion and metastasis inducing TIAM1 protein; T-cell lymphoma invasion and metastasis 1; T-lymphoma invasion and metastasis-inducing protein 1; TIAM-1
Gene Aliases: AI847750; D16Ium10; D16Ium10e; TIAM1
UniProt ID: (Human) Q13009