This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
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MA5-15855 targets OTX2 in indirect ELISA, IF, IHC, and WB applications and shows reactivity with Human samples.
The MA5-15855 immunogen is purified recombinant fragment of human OTX2 expressed in E. Coli. .
MA5-15855 detects OTX2 which has a predicted molecular weight of approximately 32kDa.
OTX2 is a 289 amino acid containing protein encoding a member of the bicoid sub-family of homeodomain-containing transcription factors. It has two known alternative splice variants with distinct isoforms though presence of other isoforms cannot be excluded. The protein is an early marker of endodermal differentiation of embryonic stem cells and may play a role in the development of the brain and the sensory organs. The protein may bind to BCD target sequence (BTS): 5-'TCTAATCCC-3'. Defects in OTX2 are the cause of microphthalmia syndromic type 5 (MCOPS5).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: homeobox Otx2; Homeobox protein OTX2; Orthodenticle homolog 2; OTX
Gene Aliases: CPHD6; E130306E05Rik; MCOPS5; OTX2
UniProt ID: (Human) P32243
Molecular Function: homeodomain transcription factor