|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Human peptide (amino acid positions 2031) coupled to KLH|
|Storage buffer||whole serum|
|Contains||0.1% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-5858 detects OVCA1 in human samples.
PA1-5858 has been successfully used in Western blot procedures.
The PA1-5858 immunogen is human peptide (amino acid positions 2031) coupled to KLH.
Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.