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|Tested species reactivity||Mouse, Rat|
|Host / Isotype||Chicken / IgY|
|Immunogen||Mouse Obestatin peptide (FNAPFDVGIKLSGAQYQQHGRAL), aa 76-98 of Ghrelin precursor.|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-9597 detects Obestatin in human, mouse and rat samples.
PA1-9597 has been successfully used in ELISA procedures.
PA1-9597 immunogen mouse obestatin peptide (FNAPFDVGIKLSGAQYQQHGRAL), aa 76-98 of Ghrelin precursor.
Obestatin is a peptide hormone. This relatively small protein (~3 kDa) is encoded by the same gene that also encodes ghrelin, also a peptide hormone. The protein produced by that gene breaks into two smaller peptides, ghrelin and obestatin by enzyme cleavage. Obestatin has been found to suppress appetite whereas ghrelin increases it. Obestatin is produced in the cells that line the stomach and small intestines. Obestatin results in decreased food intake and reduces the gastric emptying activities. It is mainly expressed in the GI tract with higher expressions in the stomach.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
appetite-regulating hormone; ghrelin; growth hormone secretagogue; growth hormone-releasing peptide; motilin-related peptide; MTLRP; obestatin; preproghrelin; proghrelin
2210006E23Rik; Ghr; Ghrl; m46; MTLRP; MTLRPAP